Stem Cell Unit
The Stem Cell Unit – Göttingen (SCU) is a technology platform at the University Medical Center Göttingen (UMG). The facility offers support in research and teaching in the fields of stem cell research for clinics and institutes of the UMG, as well as for university and extra-university research institutions of the science center Göttingen and beyond.
Key offers of the Stem Cell Unit
- Generation, cultivation, characterization, genome editing and differentiation of patient-specific iPS cells
- Responsibility for and coordination of the biobank for patient-specific iPS cell lines and iPS derivatives
- Consultation, provision of infrastructure, devices and protocols, support in the planning of projects, the design of experiments, and in learning the required range of methods
- support in the application for grants and ethical evaluations
Laboratory services
- Reprogramming in iPS cells
- Establishing of patient-specific primary cell cultures
- Reprogramming of patient-specific fibroblasts or mononucleated blood cells into iPS cells (non-integrating method, feeder- and serum-free culture conditions)
- Characterization of generated iPS cell lines including the analysis of pluripotency and differentiation potential, as well as analysis of genome stability
- Genome editing of iPS cells according to latest technologies: gene knockout, gene knock-in, and SNP insertion approaches by CRISPR/Cas9
- iPS cell differentiation in various cell types: currently primarily in functional cardiomyocytes
- Stem cell biobank: Provision of patient-specific iPS cell lines and derivatives thereof
All services offered are carried out according to established and validated SOPs and include the planning and execution of projects, as well as a primary evaluation of results.
Contact
Please contact us for detailed information and consultation.
Office: UMG 0.D2 604 / Lab: UMG 4.E2 200
Group leader
contact information
- telephone: +49 551 3964280
- e-mail address: lukas.cyganek(at)gwdg.de